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diagnosis differential algorithm causes alkalosis hypokalemia management potassium bartter chloride gout low metabolicalkalosis neurology rhabdomyolysis treatment uricacid workup acute aids
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome • Urine Chloride • Urine Ca/Cr ratio Dr. Krithika
Differentiating Gitelman ... syndrome • Urine ... Chloride • Urine ... krithicism #Gitelman ... #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... (late) • High Urine ... , Gitelman Syndrome ... #Primary #Metabolic ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Primary Metabolic ... hyperaldosteronism • Low Urine ... (late) • High Urine ... , Gitelman Syndrome ... Diagnosis #Algorithm #Nephrology
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
loop of Henle Gitelman ... Syndrome: Distal ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... → Hypokalemia Metabolic ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Low intake • Metabolic ... Renal Losses: • Metabolic ... SAME, Cushing Syndrome ... , Gitelman syndrom ... potassium #low #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Causes of Metabolic ... Diagnosis Algorithm Urine ... diuretic use Urine ... BP = Bartter's Syndrome ... , Gitelman's Syndrome
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... LiCl use The urine ... Urine chloride is ... #Algorithm #nephrology
Approach to Elevated Bicarbonate (HCO3) Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?) (+)
Gas) (-) Likely Metabolic ... Alkalosis Urine ... Volume Contraction Urine ... Barter, or Gitelman ... Syndrome Unremarkable
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... • Diarrhea A urine ... Pressure: - Metabolic ... , Gitelman syndrome ... differential #potassium #nephrology
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