16 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
ADH promotes Urea ... Osmolarity 2) Urine ... Sodium 4) Serum ... Low Uric Acid → SIADH ... #nephrology #sodium
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
uric acid <4 • SIADH ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... hyperaldosteronism • Low Urine ... (late) • High Urine ... , Gitelman Syndrome ... #Nephrology #Causes
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... volume overload Urea ... promoting passive sodium ... Saline: • If Urine ... #hyponatremia #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
administered • This can cause ... Urea powder • Induces ... promoting passive sodium ... 0.9% NS • If Urine ... #hyponatremia #nephrology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
treat underlying cause ... cirrhosis, nephrotic syndrome ... , SSRIs) - SIADH ... #diagnosis #nephrology ... #sodium
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... , Gitelman syndrome ... the indicated causes ... sodium is typically ... #Algorithm #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... Urine Na+K / serum ... Cirrhosis, Nephrotic syndrome ... #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... A urine K/Cr ratio ... • Diarrhea A urine ... , Gitelman syndrome ... differential #potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... Hypocalciuria (spot urine ... #nephrology #management ... #pathophysiology