10 results
Pathways Involved in Protein and Amino Acid Metabolism in Chronic Kidney Disease. The tricarboxylic acid (TCA)
reactions that can ... metabolize amino acids ... Urea is synthesized ... through the urea ... AminoAcidMetabolism #Pathways #NEJM
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... enhancement on CT ... periventricular areas ... effect/Edema • EBV ... differential #diagnosis #AIDS
Lymphadenopathy - Differential Diagnosis Algorithm
Localized: 
 • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
• Cervical: EBV ... Axillary: Infection (Cat ... scratch, Tularemia), Breast ... Infection: Acute HIV, EBV ... Anti-epileptic drugs (AEDs
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
antibody, Anti-GBM ... EGPA • ESR and CRP ... Other tests: • CT ... recent DAN) • EMG/NCS ... seen on chest CT
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... mononuclear cells in the CNS ... proliferation • ARVs can ... volume • Patchy areas ... disorder #dementia #AIDS
Hypertrophic Pachymeningitis - Differential Diagnosis Framework

Pachymeningitis is a rare condition that causes areas of a layer
This thickening can ... Neurosyphilis • CNS ... pachymeningitis • CNS ... metastases CT ... thrombosis CT
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... involvement • 30%: CNS ... leukostasis syndrome: CNS ... Intracellular Urate
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Acquired Pneumonia (CAP ... chest pain (LR + NS ... Uremia (blood urea ... radiograph or CT ... Obtain in severe CAP
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
• Pleuritic CP ... • CT: Halo sign ... • Lung Exam: Can ... Lymphadenopathy, CNS ... Infections #HIV #AIDS
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
inflammatory infiltrate can ... CNS involvement: ... Birbeck granules (EM ... Imaging: X-rays, CT ... PET-CT / MRI: Staging