32 results
Paths to Defective Homologous Recombination DNA Repair in Breast Cancer. Each individual mutation or epigenetic aberration
DNA Repair in Breast ... common feature of breast ... cancer #Pathophys #Honc ... BreastCancer #DNARepair #NEJM
Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer - Progression-free Survival in the Intention-to-Treat Population.
III Non–Small-Cell ... the Intention-to-Treat ... #EBM #Honc #PACIFIC ... Durvalumab #NSCLC #NEJM
Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer #EBM #Honc #Alectinib #Crizotinib #ALK #ALKPositive #NSCLC
ALK-Positive Non–Small-Cell ... Lung Cancer #EBM ... #Honc #Alectinib ... VisualAbstract #NEJM
Lymphadenopathy - Differential Diagnosis Algorithm
Localized: 
 • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
• Cervical: EBV ... scratch, Tularemia), Breast ... Infection: Acute HIV, EBV ... Angioimmunoblastic T-cell
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Rapidly rising blast ... BM • Bulky lymphadenopathy ... • Cytopenia -> BM ... • CML -> AML: Blast ... Intracellular Urate
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
HAV, HCV, HEV, EBV ... Infiltration- often breast ... CA, small cell
Radiation-Induced Angiosarcoma after Breast-Cancer Treatment - Physical examination revealed an area of skin 10 cm in
Angiosarcoma after Breast-Cancer ... the dermis and breast ... Clinical #Derm #Honc ... #Angiosarcoma #Breast ... Radiation #Microscopy #NEJM
Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma - Recurrence-free Survival in the
the Intention-to-Treat ... Population #EBM ... #Honc #Nivolumab ... Ipilimumab #Melanoma #NEJM
Melanoma of the Foot - The physical examination revealed a well-defined, fleshy, reddish plaque measuring 2
examination revealed a well-defined ... surface and black areas ... Derm #Podiatry #Honc ... Melanoma #Foot #NEJM
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
creatinine by at least ... Necrosis (Epithelial cell ... multiple myeloma) • Urate ... Glomerulonephritis • Anti-GBM