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Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... Lysis Syndrome (TLS ... ) Tumor Cell Lysis ... Precipitation => • Urate ... Hypocalcemia • Hyperkalemia
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
of neoplastic cells ... hyperuricemia, #hyperkalemia ... , #hyperphosphatemia ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS