11 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis ... PSC - Other biliary ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... intralobular bile ducts causes ... Drug-induced cholestasis, Primary ... malignancy #Primary ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... not required in all ... unclear, or if a primary ... hematologic disorder ... #Workup #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... obstruction, Primary ... , Primary sclerosing ... Diagnosis #Algorithm #hepatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... EPO-independent (primary ... up EPO levels Primary ... always a good idea ... #hematology
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... line therapy if ALP ... disease #PBC #Primary ... #Management #Treatment ... #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview: ALL ... -> AML: Blast crises ... + distinctive primary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... Primary HLH: - ... trigger • Almost all ... autoimmune disease, treatment ... #management #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... involve one, two, or all ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology