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diagnosis pediatrics peds signs symptoms 21hydroxylasedeficiency 21ohd addisons brudzinskis clinical complications cushings diabetes diabeticketoacidosis disease dka examination genetics glftap hypercortisolism
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski) Brudzinski's sign is characterized
in Meningitis ( ... Passive neck flexion causes ... patients with meningitis ... While the pathophysiology ... #Video #PhysicalExam
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 Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... - (Neisseria meningitidis ... addisons #disease #endocrinology ... #diagnosis #signs
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... non-arousable, decr urine ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
patient has good renal ... function/urine ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
For pituitary masses ... Signs / Symptoms ... Post-nasal drip • Meningitis ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
↑ 24-hour urine ... the abdomen for adrenal ... tumors • The adrenal ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Newborn Infant - Routine Examination Birthweight, gestational age and birthweight percentile are noted. General observation Of the baby's
is also a late sign ... of meningitis. ... are observed for signs ... intra-abdominal masses ... Newborn #Infant #PhysicalExam
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... Ca2+] load, Incr urine ... Skull expansion causes ... PagetsDisease #pathophysiology ... #diagnosis #signs
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