17 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
in Meningitis ( ... Passive neck flexion causes ... patients with meningitis ... While the pathophysiology ... #Video #PhysicalExam
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
no respiratory cause ... , sepsis, PNA, meningitis ... ingestion/exposure Symptoms ... Resuscitation 2) Urine ... diagnosis #management #Treatment
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
Coltivirus Symptoms ... Photophobia • Nausea ... influenzae Symptoms ... Acute meningeal signs ... established by CSF or urine
Syphilitic gummas in Tertiary syphilis
Tertiary syphilitic gummas may mimic basal cell carcinoma. The gummatous tumors are
treated, in most cases ... Without treatment ... though there are no signs ... or symptoms. ... syphilis #clinical #photo
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
adenomas that require treatment ... For pituitary masses ... Signs / Symptoms ... Post-nasal drip • Meningitis ... mnemonic #GLFTAP #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Dehydration • Symptoms ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... renal function/urine ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... DiabeticKetoacidosis #DKA #pathophysiology
Hypertonic Saline for Treatment of Hyponatremic Encephalopathy
1) 100 ml bolus of 3% NaCl over 10 min.
Hypertonic Saline for Treatment ... Symptoms improve ... improved headache and nausea ... L. 5) Monitor urine ... output for signs
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
/Symptoms: • Usually ... be present or signs ... Pathophysiology: ... present • UA and Urine ... data • Early treatment
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... non-arousable, decr urine ... #21HydroxylaseDeficiency #21OHD #pathophysiology