13 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
syndrome—due to GBM ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... sediment - WBC/RBC casts ... proliferative • Anti-GBM ... #Proteinuria #Nephrology ... Diagnosis #Algorithm #Causes
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome (GBS ... Incidence: 1 to 2 cases ... can vary from mild ... the underlying pathophysiology ... diagnosis #management #neurology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... arbitrarily defined as urine ... cell/white cell casts ... because nephritic urine ... nephrotic #syndrome #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
antibody • Urine ... : UA, Urine protein ... Goodpasture's cause ... hematuria, RBC casts ... • IF staining patterns
Subacute hypersensitivity pneumonitis
The key findings in the subacute hypersensitivity pneumonitis are:
ill-defined centrilobular nodules of ground-glass opacity
opacity (80% of cases ... ) or mosaic pattern ... There are ill-defined ... #Clinical #Radiology ... #CTChest #Hypersensitivity
On the left a chest film of a 19 year old patient with Langerhans cell histiocytosis.
The
film of a 19 year old ... was caused by multiple ... cysts. ... #Clinical #Radiology ... #CXR #CTChest #
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... • Weakness: mild ... management #treatment #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... • 75-90% of cases ... Abnormal in 50% of cases ... • Infectious causes ... diagnosis #management #neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
encephalitis, eastern ... Powassan, louping ill ... Photophobia • Nausea ... established by CSF or urine ... differential #diagnosis #neurology