13 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... to GBM disruption ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... sediment - WBC/RBC casts ... proliferative • Anti-GBM ... Minimal change disease ... #Proteinuria #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... hemolytic-uremic syndrome ... cell/white cell casts ... Nephrocalcinosis causes ... #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... antibody • Urine ... Goodpasture's cause ... hematuria, RBC casts ... diagnosis #management #treatment
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
vast majority of cases ... Measure urine osmolality ... demyelination syndrome ... vaptans (HF/liver disease ... #management #nephrology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... can vary from mild ... the underlying pathophysiology ... and cauda equina TREATMENT
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Weakness - Dark urine ... Cast formation: ... disease 2. ... #treatment #nephrology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... • Weakness: mild ... Treatment: • Plasmapheresis ... #neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Pathophysiology ... Treatment: • ... Baclofen • Severe Disease ... #neurology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... hyperglycemia —+ mild ... hypertension (90% of cases ... ↑ 24-hour urine ... #Cushings #Syndrome