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diabetes diagnosis anticonvulsants cushings diabeticketoacidosis differential dka dm2 dpp4 hypercortisolism inhibitors management mechanism moodstabilizers nephrology psychiatry rhabdomyolysis sideeffects signs summary
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Systemic effect -> Nausea ... vomiting, diarrhea, hyponatremia ... pruritus, weight gain ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Toxicities: • Joint pains ... not definitively cause ... DPP4 #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
out of cells may cause ... renal function/urine ... • Abdominal pain ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Weakness - Dark urine ... - Abdominal pain ... Hyperuricemia • Hyponatremia ... hour with goal urine
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
, oral cavity) Caused ... Dyslipidemia • Weight gain ... is decreased), hypernatremia ... ↑ 24-hour urine ... signs #symptoms #endocrinology
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