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diagnosis sideeffects anticonvulsants antipsychotics cushings diabetes differential dm2 dpp4 firstgeneration hypercortisolism inhibitors management mechanism mechanisms moodstabilizers nephrology pathophysiology rhabdomyolysis signs
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Systemic effect -> Nausea ... vomiting, diarrhea, hyponatremia ... pruritus, weight gain ... Pathophysiology #Psychiatry ... #Pharmacology
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Toxicities: • Joint pains ... not definitively cause ... DPP4 #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Weakness - Dark urine ... - Abdominal pain ... Hyperuricemia • Hyponatremia ... hour with goal urine
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
brain • Weight Gain ... arterioles -> less able ... , and/or limbs caused ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
, oral cavity) Caused ... Dyslipidemia • Weight gain ... is decreased), hypernatremia ... ↑ 24-hour urine ... signs #symptoms #endocrinology
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