13 results
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
are the newest class ... kidney), which causes ... glucose in the urine ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... of hypotonic hyponatremia ... volume-based algorithm Urine ... Uosm <100): Renal Losses ... differential #diagnosis #table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... : • Triad of symptoms ... • Other symptoms ... Hyperuricemia • Hyponatremia ... Diagnosis #Management #causes
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Medication Guide Classes ... Diabetes #Mellitus #DM2 ... #Medications #pharmacology ... #comparison #table
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
countries (11-24 cases ... Americans (18-71 cases ... mortality: 9-14 cases ... survival is 93-95% Pathophysiology ... are not caused
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... renal function/urine ... anion gap until it closes ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... non-arousable, decr urine ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Dermatomyositis) AKI - Pathophysiology ... hour with goal urine ... per day until stable ... Management #Summary #causes
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
heat illness → Hypernatremia ... Collapse: • Pathophysiology ... Syncope • Signs/Symptoms ... and electrolyte losses ... differential #diagnosis #causes
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Kidney stones caused ... Heart Association class ... and euvolemic hyponatremia ... Diuresis #Nephrology #Pharmacology ... #Medications #Table