22 results
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... uric acid <4 • SIADH ... Glucocorticoid deficiency, Primary ... #algorithm #diagnosis ... #sodium #low #nephrology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Diagnosis Algorithm ... treat underlying cause ... Solute Intake - Primary ... , SSRIs) - SIADH ... diagnosis #nephrology #sodium
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Algorithm Hypertonic ... OFF (UNa > 30): SIADH ... (UOsm < 100): Primary ... #Algorithm #diagnosis ... #sodium #nephrology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
angiography • Primary ... Oral sodium loading ... urine aldosterone ... . 24-h urinary free ... repaired) • Primary
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... Algorithm UOsm ... Inappropriate - Consider: SIADH ... Vasopressin-independent - Consider: Primary ... #causes #nephrology
A lazy man's classification of hyponatremia
There are two possible approaches to the diagnosis of hyponatremia: .
essentially the same tests ... serum osmolality, urine ... osmolality and urinary ... sodium). ... the patient has SIADH
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... Urine Na+K / serum ... , Renal Sodium loss ... water intake (Primary
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
- Urinary Chloride ... Algorithm Cl- ... the indicated causes ... #Urinary #Chloride ... #urine #Algorithm
Hyponatremia - Diagnostic Evaluation Algorithm

Step 1: Consider whether Posm may actually be normal or elevated
Step 2:
Evaluation Algorithm ... Check Uosm and/or Urine ... Consider additional tests ... Step 5: If SIADH ... considered likely, the cause
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
Primary Polydipsia ... heavy smokers Primary ... Insipidus, Impaired Urinary ... , Urine Sodium ... Alert_Oriented3 #Primary