12 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Diagnosis Algorithm ... Utilizing Uric Acid ADH ... 2) Urine Osmolarity ... 3) Urine Sodium ... Low Uric Acid → SIADH
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) Sodium ... ) Naturiesis → diuresis ... Hypovolaemia → ADH ... → Increased urine ... diagnosis #nephrology #hyponatremia
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Repeat the sodium ... volume loss - diuretics ... EUVOLEMIC • SIADH ... HYPERVOLEMIC • CHF ... Diagnosis #Workup #Algorithm
Hyponatremia Treatment Algorithm

CHF, Cirrhosis - Fluid restriction
SIADH - Fluid restriction
 - Consider salt tablets if etiology
Hyponatremia Treatment ... Algorithm CHF ... Fluid restriction SIADH ... status turns off ADH ... #Treatment #Algorithm
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... restriction alone in SIADH ... , Renal Sodium loss ... Insufficiency, Cerebral
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Algorithm Hypertonic ... OFF (UNa > 30): SIADH ... , Medications (diuretics ... Reset osmostat, Cerebral ... #sodium #nephrology
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
, urine sodium concentration ... and urine osmolality ... consequence of cerebral ... Measured urine sodium ... #hyponatremia #ADH
A lazy man's classification of hyponatremia
There are two possible approaches to the diagnosis of hyponatremia: .
, urine osmolality ... and urinary sodium ... the patient has SIADH ... or cerebral salt ... #Algorithm #Differential
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
majority of cases, ADH ... Measure urine osmolality ... volume status (EABV ... include vaptans (HF ... management #nephrology #sodium
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
promoting passive sodium ... Saline: • If Urine ... osmolality < 538 ... antagonists: • Blocks ADH ... #nephrology #treatment