13 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... Utilizing Uric Acid ADH ... Sodium 4) Serum ... Low Uric Acid → SIADH
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Algorithm Hypertonic ... : • ADH ON (UOsm ... - RAAS ON (UNa ... > 30): SIADH, Medications ... #sodium #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... Urine Na+K / serum ... or Ineffective (UNa ... (Uosm ≥100): SIADH
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
electrolyte abnormality caused ... among the possible causes ... Measured urine sodium ... #hyponatremia #ADH ... EBV #potomania #SIADH
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... Diagnosis Algorithm ... treat underlying cause ... , SSRIs) - SIADH ... diagnosis #nephrology #sodium
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
promoting passive sodium ... Saline: • If Urine ... osmolality < 538 AND UNa ... antagonists: • Blocks ADH ... #nephrology #treatment
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... water loss, Serum Sodium ... 145 mmol/L High Urine ... kg • Diabetes Insipidus ... #Causes
Hyponatremia - Diagnostic Evaluation Algorithm

Step 1: Consider whether Posm may actually be normal or elevated
Step 2:
Evaluation Algorithm ... Check Uosm and/or Urine ... status and measure UNa ... tests Step 5: If SIADH ... considered likely, the cause
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
ADH suppression ... with suppressed ADH ... Pseudohyponatremia, SIADH ... Osm, Serum Sodium ... , Urine Sodium
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... promoting passive sodium ... osmolality < 538 AND UNa ... vaptans) • Blocks ADH ... #Management #hyponatremia