13 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... transformation to acute leukemia ... Myelodysplastic #Syndrome ... #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... Hyperviscosity Syndrome ... Vomiting, decreased urine ... coma SIADH: • Hyponatremia ... #differential #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Richter’s Syndrome ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... chlorambucil) 2) Purine ... #oncology #hematology ... #hemeonc #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Management Summary Causes ... Dermatomyositis Clinical ... Weakness - Dark urine ... Hyperuricemia • Hyponatremia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology ... #oncology
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... 100 mOsm/kg = Urine ... capillary leak syndrome ... algorithm #nephrology #oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... excretion (e.g., urine ... of lactate as a clinical ... / hypoxemia -> focus ... - Compartment syndrome