8 results
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... #nephrology #pathology ... comparison #table #diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... polyangiitis, Microscopic ... ab, anti-GBM ab ... #differential #diagnosis ... #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause ... #management #treatment
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... ) Classification ... number of sites of disease ... #classification ... hematology #oncology #management
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
- but 5% have anti—muscle-specific ... More likely to cause ... glucocorticoids - can cause ... Hospital of Baltimore IM ... #management #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... Dx: GPA, EGPA, microscopic ... #rheumatology #classification
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
levels • NMO-IgG (anti-AQP4 ... • Infectious causes ... Brucellosis - Dengue, EBV ... AntiCRMP IgG, Anti-Hu ... #management #neurology