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diagnosis differential rheumatology vasculitis acute aki ana antibodies antibody antineutrophil antinuclear classification comparison glomerular injury kidney management pathology syndromes table
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Renal Syndromes ... sclerosis • Anti-Glomerular ... ab, anti-GBM ab ... #Renal #Syndrome
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
cases • Sjögren syndrome ... Vasculitis: • Microscopic ... • Renal-limited ... + 90% • Anti-GBM ... disease - MPO>PR3
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... • Lupus ISN/RPS ... Amyloid RPGN • Anti-GBM ... #diseases #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Diagnosis Framework PRE-Renal ... • Vascular • Glomerular ... : ANCA, Immune-complex ... disease, Anti-GBM ... Differential #Diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... diseases with pulmonary ... antibody, Anti-GBM ... usually low in anti-GBM
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and renal abnormalities ... -ANCA): • Microscopic ... glomerulonephritis) • Anti-GBM ... Dx: GPA, EGPA, microscopic ... • Urinalysis (Renal
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
and renal abnormalities ... • Kidneys: Non-glomerular ... -ANCA)): Microscopic ... abdominal pain and GN Anti-GBM ... vasculitis • Cogan syndrome
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