44 results
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... RPGN • Anti-GBM ... #nephrology #pathology ... comparison #table #diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... polyangiitis, Microscopic ... anti-ANCA ab, anti-GBM ... #differential #diagnosis ... #nephrology
Legionnaire's Disease - Extrapulmonary organ involvement: CNS: Mental confusion, encephalopathic, headache. Cardiac: Relative bradycardia. GI: Loose
Legionnaire's Disease ... Renal: Microscopic ... insufficiency #Diagnosis ... #IM #InfectiousDisease
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... fresh at time of microscopy ... Red cell casts - Diagnostic ... #Atlas #key #diagnosis ... #nephrology #casts
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
- Differential Diagnosis ... Wegener's) • P-ANCA: Microscopic ... Strauss) Anti-GBM ... #differential #diagnosis ... #nephrology #causes
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
of Glomerular Diseases ... • Breaks in GBM ... #Glomerular #Diseases ... differential #spectrum #diagnosis ... #nephrology #nephritic
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... cells on urine microscopy ... disease • ... • Pauci-immune disease ... #Differential #Diagnosis
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
and Differential Diagnosis ... intrinsic renal disease ... neck, prostatic) #Diagnosis ... #EM #IM #Urology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... Microscopic polyangiitis ... (TTG) - Celiac disease ... Anti-GBM - Goodpasture's ... #diagnosis #table
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and Disease ... Advanced kidney disease ... edgarvlermamd - Nephrology ... #Differential #Microscopy ... #Diagnosis #Nephrology