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diagnosis differential rheumatology vasculitis renal algorithm anti antigbm basement classification disease giomeruiar management membrane progressive rapidly rpgn syndrome syndromes treatment
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Glomerulonephritis ... With associated pulmonary ... Disease (Goodpasture's ... Negative IF): • PR3
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... Anti-basement membrane: Goodpasture ... renal failure (glomerulonephritis ... cause pulmonary ... FINDINGS: • U/A: microscopic
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... polyangiitis, Microscopic ... Basement Membrane: Goodpasture's ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
rapidly progressive glomerulonephritis ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... AntiGBM #diagnosis #nephrology ... #pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
-ANCA): • Microscopic ... and/or pulmonary ... tract, and often causes ... ) • Anti-GBM - ... Dx: GPA, EGPA, microscopic
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
-ANCA)): Microscopic ... , pauci-immune glomerulonephritis ... tract, and often causes ... pain and GN Anti-GBM ... Mononeuropathy, Glomerulonephritis
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