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diagnosis differential pathology algorithm clinical electronmicroscopy glomerulonephritis membranous proteinuria pulmonary renal rheumatology sem vasculitis causes classification comparison diseases glomerulus management
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Nephrotic syndrome ... RPGN • Anti-GBM ... #diseases #nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... anti-ANCA ab, anti-GBM ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Stage II Membranous Glomerulonephritis on Electron Microscopy This eyeSCANdy image shows acellular scanning EM of a glomerulus
of a glomerulus ... appearance of GBM ... glomerulonephritis #MGN ... #stage2 #GBM #ElectronMicroscopy ... SEM #clinical #nephrology
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 Stage IV Glomerulonephritis on Electron Microscopy This image shows acellular scanning EM of glomerular capillary loops from
Glomerulonephritis on Electron Microscopy ... of glomerular capillary ... completely bridged GBM ... #MGN #stage4 #ElectronMicroscopy ... SEM #clinical #nephrology
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 Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... • Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... = glomerular basement ... hemolytic-uremic syndrome ... proteinuria #nephrotic #syndrome ... #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... antibody, Anti-GBM ... usually low in anti-GBM ... hypercellular glomeruli ... in crescentic GN
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... PR3-ANCA): • Microscopic ... glomerulonephritis) • Anti-GBM ... Vasculitis - Skin, glomeruli ... : - Kidneys: glomerular
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
• Kidneys: Non-glomerular ... (PR3-ANCA)): Microscopic ... Anti-GBM (10 - ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
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