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V/Q Mismatch Physiology

by Dr. Lizzy Hastie @LizzyHastie

#VQMismatch #pathophysiology #diagnosis #pulmonary
V/Q Mismatch Physiology ... LizzyHastie #VQMismatch
Lynch Syndrome:
 • "CRC + Endometrial/Ovarian + Stomach + Urinary → Lynch Syndrome"
 • Autosomal Dominant,
EPCAM genes → Mismatch
Hypoxemia Differential Diagnosis Algorithm by A-a Gradient

Normal A-a Gradient:
 • ↓ Atmospheric pressure
 • Hypoventilation: CNS
Alveolar • V/Q Mismatch
Causes of Hypoxemia- Differential Diagnosis Algorithm
Ventilation/perfusion Mismatch
 • Airway Disease (Asthma, COPD)
 • Vascular (PE*)
 •
Ventilation/perfusion Mismatch
Hypoxemic Respiratory Failure - Differential Diagnosis Framework
DECREASED INSPIRED OXYGEN
 • Low PATM Can decrease first part
common than VIQ mismatch ... PERFUSION (V/Q) MISMATCH
Evolution of stroke on CT and MRI. 

Day 1: NCHCT demonstrates obscure left insular cortex. No
The PWI/DWI mismatch
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
and more • V/Q Mismatch
TISSUE APPEARANCES ON 
MUSCULOSKELETAL ULTRASOUND 

Bone:
 
Bone is represented as a very bright structure and appears
acoustic impedence mismatch ... #POCUS #Atlas #Clinical
Chattering on ECMO
What is chattering? If you look closely at this video clip, the tubing is
This is due to a mismatch ... ECMO #chatter #clinical
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
shunt (Type 2) Clinical ... Hypoxemia - V/Q mismatch