48 results
Approach to Von Willebrand disease (VWD)

By Matthew Ho, MD PhD @MatthewHoMD

#VWD #Von #Willebrand #VonWillebrand #disease #hematology
Willebrand disease (VWD ... MatthewHoMD #VWD
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
also be seen in vWD ... differentiate vWD ... BS by measuring vWF
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Coagulopathy: DIC, vWD
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Diagnosis VWF ... (Quantity of VWF ... considered to be low) VWF ... of this plasma VWF ... (differentiate VWD
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Willebrand disease (VWD
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
angioedema • vWD
Patch dehiscence (post surgical correction of congenital VSD) on Echocardiogram

Ivan Stankovic, MD, PhD @Ivan_Echocardio

#VSD #Patch #dehiscence
of congenital VSD ... Ivan_Echocardio #VSD
Cardiac Auscultation Maneuvers for Murmurs
Maneuvers result in INCREASED murmur:
 • Inspiration - Right-sided
 • Valsalva -
regurgitation, VSD ... regurgitation, VSD
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
xarelto #DOAC #vWF
Stroke Volume & Cardiac Output Measurement on POCUS
Accurately measure LVOT diameter:
1. Obtain PLAX 
2. Zoom to
Run PWD trace 4 ... Trace around PWD