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Approach to Von Willebrand disease (VWD) By Matthew Ho, MD PhD @MatthewHoMD #VWD #Von #Willebrand #VonWillebrand #disease #hematology
Willebrand disease (VWD ... MatthewHoMD #VWD
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
also be seen in vWD ... differentiate vWD ... BS by measuring vWF
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Diagnosis VWF ... (Quantity of VWF ... considered to be low) VWF ... of this plasma VWF ... (differentiate VWD
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... Autoantibodies to vWF ... Autoimmune disease • vWF ... Syndrome #Diagnosis #Management
Patch dehiscence (post surgical correction of congenital VSD) on Echocardiogram Ivan Stankovic, MD, PhD @Ivan_Echocardio #VSD #Patch #dehiscence
of congenital VSD ... Ivan_Echocardio #VSD
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 Cardiac Auscultation Maneuvers for Murmurs Maneuvers result in INCREASED murmur: • Inspiration - Right-sided • Valsalva -
regurgitation, VSD ... regurgitation, VSD
Cardiac Valve Replacement - Anticoagulation INR Targets and Antiplatelet by Valve Type Bioprosthetic valves require at least
(2017 AHA/ACC VHD ... (2017 AHA/ACC VHD ... #Management #Cardiology
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
xarelto #DOAC #vWF
Stroke Volume & Cardiac Output Measurement on POCUS Accurately measure LVOT diameter: 1. Obtain PLAX 2. Zoom to
Run PWD trace 4 ... Trace around PWD
Shock and Vasoactive Drugs 1) Determine type and etiology of shock • Distributive: Sepsis, Anaphylaxis, Neurogenic
muscle rupture, VSD ... inopressors #diagnosis #management
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