28 results
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Disease, Rheumatoid Vasculitis ... Disease and ILD Complications ... RA #diagnosis #rheumatology ... #signs #symptoms
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Purpura - Diagnostic Algorithm ... Pathophysiology: ... trauma, infection, vasculitis ... #Diagnosis #Dermatology ... #Differential #
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Ill-appearing, vital sign ... #Diagnosis #Dermatology ... Color #Targetoid #Algorithm ... #Differential #
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... WBC >100k, + lab signs ... sudden death • Lab values ... diagnosis #management #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... organ-specific signs ... or symptoms (eg ... #Differential # ... diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm ... #rheumatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... Returning Traveler’ algorithm ... thin smear • Signs ... biopsy • Lab values ... supporting hematologic
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... and ophthalmic complications ... systemic sx + signs ... or sed rate): Value ... very remarkable w/differential