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diagnosis gh treatment acromegaly barre excess feedbackloop gitelman guillain guillainbarre hematology hypokalemia leukostasis lysis nephrology neurology overproduction pituitary signs symptoms
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
deficiency: - Short ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Carpal Tunnel Syndrome ... fraction • HTN #GrowthHormone ... signs #symptoms #endocrinology ... #pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... : • Pathophysiology ... sudden death • Lab values ... TLS #diagnosis #management
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... • Weakness: Starts ... Miller Fisher Syndrome ... #diagnosis #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Diagnosis and Management ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... #Endocrinology ... #Treatment #Pathophysiology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Gitelman's syndrome ... Hypocalciuria (spot ... diagnosis #nephrology #management ... #pathophysiology
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