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hepatology algorithm classification injury lactate nephrology acidosis acute alkaline alp cholestatic dehydrogenase elevated enzymes examination failure fever heat heatstroke hematology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
) - Causes of Hepatocellular ... Injury • AST/ALT elevation ... skeletal muscle and kidney ... • R value = (ALT ... #differential #
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... Intestine - Other causes ... Intestine • Kidney ... Pregnancy - Renal
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Causes of Acute ... Kidney Injury ( ... Urethral stricture/valves ... /phimosis #Diagnosis ... Postrenal #Failure #Differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... extrahepatic source - Tests ... Enzyme Elevation
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... to bolus these values ... tests before beginning ... #Differential # ... Diagnosis #causes
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... Mild-to-moderate elevation ... WBC count and differential ... the presence of renal
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Tachycardia - N/V - Abdominal ... ULN • AST/ALT Elevation ... nephrotoxicity to kidney
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Diagnosis Framework ... involvement: Muscles, Kidneys ... - Headache - Abdominal ... acidosis - CPK elevation ... #diagnosis #causes
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Diagnosis Framework ... RBCs, muscle, liver ... , and kidney • ... - Prosthetic valves ... Idiosyncratic LDH Elevation
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... tract, and often causes ... - GI tract: abdominal ... retinopathy Lab Tests ... • Urinalysis (Renal
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