25 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... decreased PLT count: CBC ... - Bone marrow evaluation ... Diagnosis #Causes #Workup ... #hematology
Age-Focused Initial Evaluation for Pyoderma Gangrenosum 

All Patients: 
 - A thorough history and physical examination
Age-Focused Initial Evaluation ... mycobacterial) - CBC ... #Gangrenosum #Workup ... #Evaluation #Age ... #Dermatology #Diagnosis
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Myelodysplastic Disorder ... bcr-able (+) ↑ WBC ... Amy Chung, MD, MSc ... #hematology #Markers
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... during medical evaluation ... or workup for specific ... 1,500 cells/µL Workup ... Differential #diagnosis #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
appreciate the value ... 21% had normal WBC ... count on initial evaluation ... #CBC #hematology ... #pathophysiology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(MCV): Average RBC ... wide range of RBC ... (BM) ablative disorders ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
hypertension • Unusual RBC ... acanthocytes - Consider RBC ... membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... Lysis Syndrome: • Pathophysiology ... sudden death • Lab values ... diagnosis #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... cholangitis #diagnosis #workup ... #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... activity - A low value ... If the value is ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology