15 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... - Bone marrow evaluation ... or if a primary hematologic ... Diagnosis #Causes #Workup ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... during medical evaluation ... or workup for specific ... 1,500 cells/µL Workup ... Differential #diagnosis #hematology
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing (and disruptors ... ) • Fracture disrupts ... Metabolic / Endocrine disorders ... #Orthopedics #msk ... #Staging #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Amy Chung, MD, MSc ... Lymphoproliferative #Disorders ... Classification #pathophysiology ... #Hematology #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
factor function • Disruptions ... Vasculitis - Collagen disorders ... deficiency Work ... Algorithm #Causes #dermatology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... Approach (when evaluation ... previously stable values ... Neurologic disorders ... #Hypertension #Workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... activity - A low value ... If the value is ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... macrophages that disrupts ... inhibitors under evaluation ... treatment #summary #rheumatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
that a one-off value ... Better call hematology ... you’ll do a good workup ... Diagnosis #Algorithm #workup ... #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
appreciate the value ... count on initial evaluation ... neutrophil #WBC #CBC #hematology ... #pathophysiology