Variability classification grading syndrome algorithm dysfunction management types activation mas

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Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of

Macrophage Activation ... Syndrome (MAS) ... IL-1 and IL-6, leading ... nervous system (CNS) dysfunction ... #Management #Hematology

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

Skin Disease Classification ... Kikuchi disease • Type-I ... erythematosus (NPSLE): • May ... mild cognitive dysfunction ... Chronic B-cell activation

Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in

recognition and management ... cytopenias and organ dysfunction ... Persistent fever, organ dysfunction ... Types of HLH • ... (often termed MAS-HLH

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