20 results
Approach to the Hospitalized Patient with Cirrhosis
1) Recognize and Manage Decompensation
 • Ascites
 • Variceal Bleeding
Decompensation • Ascites ... • Variceal Bleeding ... • Hepatic Encephalopathy ... 2) Manage Common ... Portosystemic Shunt • Liver
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
of portal HTN: ascites ... to non-cirrhotic ... portal HTN: • Ascites ... sarcoidosis) • Liver ... metastasis • Fatty liver
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... Liver disease ... - Cirrhosis ... - Acute fatty liver ... #Causes #diagnosis
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... Hypertension - Hepatic ... : • Cirrhosis ... disease • Acute liver ... Hypertension - Post-Hepatic
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
deficiency in the common ... (e.g. heparin contamination ... inhibitors to the common ... • Reduced liver ... #differential #hematology
Common Malignancies That Cause Ascites
The most common malignancies causing ascites are ovarian cancer, pancreatic cancer, gastric
Common Malignancies ... That Cause Ascites ... The most common ... Cancer - Most common ... hypertension or hepatic
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
deficiency • Liver ... meningitidis - Varicella ... Cholesterol emboli • Septic ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Female:Male 9:1 • Common ... intralobular bile ducts causes ... /Liver failure ... or higher • Liver ... malignancies, Hepatic
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Most common ... sites: hip, shoulder ... Osteomyelitis / Septic ... #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... inhibitors to the common ... Reduced liver synthesis ... #differential #hematology