12 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... meningitidis - Varicella ... reactions • Erythema gangrenosum ... #hematology #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
PAN Pyoderma gangrenosum ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #differential #diagnosis ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
resemble pyoderma gangrenosum ... Differential Diagnosis ... • Goodpasture syndrome ... #rash #diagnosis ... #rheumatology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... SAPHO syndrome ( ... Varicella 3. ... Pyoderma gangrenosum ... #Dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
thrombophlebitis, pyoderma gangrenosum ... lesions, pyoderma gangrenosum ... response to local skin ... #diagnosis #management ... signs #symptoms #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... dermatosis • Pyoderma gangrenosum ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... #Differential #Diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lower-extremity joints Diagnosis ... • A clinical diagnosis ... #Rheumatology # ... diagnosis #management ... #Dermatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
: • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology ... #hematology #diagnosis ... #management
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... and Management ... Malignancy - Immunologic ... #hematology #differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... Constitutional Syndromes ... Anemia #oncology #hematology ... #diagnosis #management