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management anticoagulation doac diagnosis malignancy vte anemia aplastic cyp3a4 hemophagocytic hlh inducers inhibitors interactions longterm lymphohistiocytosis pglycoprotein pharmacology summary table
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... for the treatment ... mass index; VTE = venous ... #Management #Hematology ... #Oncology
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 Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... incidental DVT or PE in cancer ... thrombosis in cancer ... #Management #Hematology ... #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... inducers #inhibitors #Chemotherapy ... #Oncology #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... B-LNH), solid cancers ... Unknown cause Treatment ... Anti-infectious, chemotherapy ... #summary #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Cytotoxic drugs/Chemotherapy ... • Epstein-Barr virus ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Longterm Venous Thromboembolism Treatment Algorithm Treat for 3 months and reassess • Isolated distal DVT (without cancer)
Longterm Venous ... Thromboembolism Treatment ... Algorithm Treat ... #Algorithm #management ... #hematology #anticoagulation
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