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diagnosis management rheumatology aplastic bandemia cardiology cbc chronic fatigue hemophagocytic hepatology hepatorenal hlh hospitalization hrs isolated lymphohistiocytosis nephrology neutropenia neutrophil
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... - Differential ... Neoplastic / Hematologic ... • Anemia • ... Tuberculosis • Epstein-Barr
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Diagnosis Algorithm ... Infection • Epstein-Barr ... Virus • Cytomegalovirus ... #Causes #Hematology
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Causes of Pericarditis ... - Differential ... Diagnosis Algorithm ... Adenovirus • Epstein-Barr ... Metabolic: • Uremia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... CMV) • Epstein-Barr ... virus (EBV) • ... #oncology #hematology
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
- Differential ... ) 3) Use MCV & clinical ... guide further evaluation ... diagnosis #hematology ... #algorithm #reticulocyte
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... count on initial evaluation ... #differential # ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus ... inhibitors under evaluation
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
- Pathophysiology ... the Journal of Clinical ... evaluations. ... #pathophysiology ... #differential #
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... CLINICAL: • Physical ... • An evaluation ... • Normocytic anemia ... normal and can help differentiate
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... Diagnosis (Clinical ... e.g., alcohol, virus ... liver transplant evaluation ... Hepatorenal #Syndrome #Hepatology
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