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diagnosis management differential neurology syndrome guillain treatment anatomy aplastic ascorbicacid b12 bells cardiology chronic cobalamin deficiency erythema fatigue gbs guillainbarre
Bell's Palsy Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
an identifiable cause ... The cause is unknown ... but its clinically ...     - Epstein-Barr ... neurology #anatomy #pathophysiology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... Tuberculosis • Epstein-Barr ... Virus • Hepatitis ... #causes
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Causes of Pericarditis ... Differential Diagnosis Algorithm ... Adenovirus • Epstein-Barr ... virus • Cytomegalovirus ... Metabolic: • Uremia
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Pathophysiology ... COVID 19 - Zika virus ... meningococcal, H1N1) Clinical ... Clinical Features
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... transplantation CLINICAL ... the underlying pathophysiology ... specific therapy, the clinician
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... immunodeficiency virus ... CMV) • Epstein-Barr ... virus (EBV) •
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Clinical Presentation ... breath, wasting, anemia ... Loss of teeth Anemia ... , or any other cause ... #Nutrition #Diagnosis
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... intrinsic factor, IF) Clinical ... wt loss • If anemia ... total body stores Evaluation ... diagnosis #management #nutrition
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus ... inhibitors under evaluation
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
- Pathophysiology ... the Journal of Clinical ... reasoning during clinical ... evaluations. ... #pathophysiology
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