20 results
Woltman’s sign on Physical Exam

53-year-old man presented with fatigue and sensitivity to cold. A physical examination
the ankle jerk reflex ... and laboratory evaluation ... confirmed a diagnosis ... #Delayed #Clinical ... #Video #Neurology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
The Neurological Evaluation ... Differential Diagnosis ... • Mutism Pathophysiology ... • Examine for signs ... Casey Albin MD @
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... and Differential Diagnosis ... investigations depending on clinical ... context and signs ... #nephrology #causes
Relative Afferent Pupillary Defect

This maneuver of intermittent light stimulus is called the alternating light test or
It is a clear sign ... the pupillary reflex ... very sensitive diagnostic ... regarding the cause ... #Clinical #Video
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Pathogenesis and clinical ... diffuse light reflex ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus ... inhibitors under evaluation
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... numbness, decreased reflexes ... Pathophysiology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
- Differential Diagnosis ... Photophobia • Nausea ... • Common clinical ... Acute meningeal signs ... #neurology #meningitis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... bladder and rectal reflex ... Injury #Syndromes #diagnosis ... #pathophysiology ... #signs #symptoms