14 results
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Malignancy Infectious ... Tuberculosis • Epstein-Barr ... Pulmonary Disease Neurologic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Infection) High ... #MCV #Classification ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... deficiency Infections ... Cytomegalovirus • Epstein-Barr ... virus • Parvovirus ... #Hematology
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
Hepatitis B Virus ... hepatitis B - Chronic ... less commonly, infection ... Interpretation #diagnosis ... #laboratory #hepatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Antineoplastic Viral Infection ... • Epstein-Barr ... Virus • Cytomegalovirus ... Idiopathic - Chronic ... Algorithm #Causes #Hematology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... to a preceding infection ... • Most common infection ... the underlying pathophysiology ... #management #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... response preceding infection ... COVID 19 - Zika virus ... Diagnosis: • ... management #treatment #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... CMV) • Epstein-Barr ... #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... autoimmune hemolytic anemia ... Malignancies • Chronic ... infections (Epstein-Barr ... hypogammaglobulinemia #immunology #hematology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... diseases - HIV infection ... hemolytic anemia ... multifactorial mechanisms Hematologic ... #Diagnosis #Differential