13 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... than females Guillain-Barre ... Pathophysiology ... bulbar muscles Guillain-Barre ... • Areflexia Guillain-Barre
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... to a preceding infection ... the underlying pathophysiology ... and cauda equina TREATMENT ... SinaiBmoreIMRes #GBS #Guillain
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... deficiency Infections ... Cytomegalovirus • Epstein-Barr ... virus • Parvovirus ... #Diagnosis #Hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Neutropenia - Differential ... Antineoplastic Viral Infection ... • Epstein-Barr ... Virus • Cytomegalovirus ... Algorithm #Causes #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... +++: Virus (EBV, ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
epidural hematoma • infections ... constipation Differential ... toon • Spinal infection ... Tethered cord • Guillain-Barre ... axial T1 and T2 Treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... CMV) • Epstein-Barr ... aplastic anemia Treatment ... Anemia #oncology #hematology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Statins), ETOH Infection ... Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... per day until stable
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
six months of treatment ... albicans • Epstein Barr ... Leishmaniasis Differential ... Treatment: ... Inflammatory #Syndrome #Differential
Tongue Pathology 

Geographic tongue, fissured tongue, and hairy tongue are the most common tongue problems and
do not require treatment ... with a candidal infection ... by the Epstein-Barr ... virus and is treated ... require biopsy to differentiate