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diagnosis aids differential hiv management neurology associated dementia disorder hand hemophagocytic hlh immune infections inflammatory iris lymphohistiocytosis neurocognitive opportunistic reconstitution
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
should be based on clinical ... Antimicrobial treatment ... Herpes Simplex Virus ... • JC-virus PCR ... opportunistic #InfectiousDiseases
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Infections+++: Virus ... salmonella, ...), Parasites
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... Virologic and immunologic ... noncompliance • Clinical ... initiation Clinical ... pleural effusions, CNS
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... and infects the CNS ... : The clinical ... syndrome of HAD ... Treatment: • HAART
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