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differential arthritis joint management oncology approach disease agglutinin aplastic causes cell classification cold common disorders erythematosus hemolytic hodgkins hypogammaglobulinemia immunodeficiency
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... IgA, IgG, IgM (CVID ... changes), high MCV anemia ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... - HIV • Immune ... (HIV) • Parvovirus ... #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... autoimmune hemolytic anemia ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... lesions Abdominal pain ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... - Autoimmune Rheumatologic ... Parvovirus B19 • HIV ... #Differential #Diagnosis ... #MSK #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint Pain ... e.g., congenital hip ... #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... anemia • Cold ... Mycoplasma, EBV, HIV ... chills, flank pain ... #hematology #diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... - parvovirus, HIV ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Additional tests: HIV ... , and low back pain ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... • Pain in LN ... Hodgkin Lymphoma Workup ... classification #hematology
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