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hematology neurology barre differential guillain hemophagocytic lymphohistiocytosis summary acromegaly activation anemia aplastic arthritis behcet dermatology disease endocrinology erythematosus gbs guillainbarre
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... • Infection should ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... Liver function tests ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Initial screening test ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
of hands/feet, knees ... , shoulders Signs ... : CLINICAL DIAGNOSIS ... exam and imaging Treatment ... #management #rheumatology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
COVID 19 - Zika virus ... Guillain-Barre Clinical ... • Weakness: Starts ... #diagnosis #management ... #treatment #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... • Epstein-Barr virus ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... and lower jaw Treatment ... #Rheumatology # ... diagnosis #management
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... and sensitive tests ... and cauda equina TREATMENT ... #diagnosis #management
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