9 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Infections+++: Virus ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... COVID 19 - Zika virus ... • Weakness: Starts ... #management #treatment
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
fibrin clot has formed ... age, which can cause ... Ddimer #dimer #pathophysiology ... #hematology #differential ... #diagnosis #age
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... #management #neurology ... #differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... in improperly folded ... - Causes progressive ... conditions listed in differential ... #management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
to be in ADHF starts ... the determined cause ... #diagnosis #differential ... #algorithm #management ... treatment #table #foamed
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
that are poorly formed ... Pinpoint-sized red spots ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
Hospitalization - Pathophysiology ... In WW2, when forced ... #pathophysiology ... #differential # ... diagnosis
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
anemia (MAHA) Pathophysiology ... Initiate ACEi (short-acting ... • Refractory cases ... Renal #Crisis #rheumatology ... #management