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diagnosis nephrology rheumatology syndrome treatment vasculitis algorithm apml cardiology causes challenges chronic classification comparison criticalcare dehydrogenase differentiation elevated endocarditis fatigue
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... , r/o infection ... reveals increasing blood ... #differential # ... diagnosis #management
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
Hematuria in Post-Renal ... : Secondary to infections ... #differential # ... diagnosis #kidney #blood ... #urine #management
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Dyspnea, Fever, Hematuria ... BAL → confirm DAH ... , rule out infection ... #differential #
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Metabolic • Renal ... • Malignancy Infectious ... Epstein-Barr Virus ... Chronic Obstructive Pulmonary ... Myasthenia Gravis Pharmacologic
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... Anaphylaxis, Acute Renal ... APML #diagnosis #management
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... deficiency of red blood ... Legionnaires disease • Pulmonary ... 94 and 84% Renal ... • Toxins • Infection
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
multiplex • Hematuria ... and renal abnormalities ... to exclude are infections ... Large Vessel: Blood ... • Urinalysis (Renal
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Mononeuritis multiplex • Hematuria ... and renal abnormalities ... pulses, bruits, or blood ... Polyarteritis Nodosa: • PAN
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Microbiology: Blood ... Cerebral > Splenic, pulmonary ... Marantic (NTBE) Differential ... Leukocytosis, anemia, and hematuria ... Endocarditis #diagnosis #management
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary Fluid resuscitation can be beneficial when required or
lower risk of renal ... Pulmonary Artery ... via cold saline injection ... • PULMONARY A ... comparison #challenges #management
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