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anesthesia anesthesiology checklist intraoperative differential hematology lupus druginduced endocrinology hyperthermia oncology sle summary syndrome acromegaly algorithm anaphylaxis anemia aplastic boop
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... asthma, allergy, drug ... glucocorticoid treatment ... #Differential #diagnosis
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
production • Treatment ... : Drugs: Ecstasy ... #Hyperthermia #comparison ... #diagnosis #management ... #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... immune deficiency, Drugs ... Treatment: • Etiological ... #management #treatment ... #summary #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment ... #rheumatology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
• Diagnostic ... thoracotomy is a better treatment ... • Inotropic drugs ... Plan definitive management ... #Management #Workup
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia • Unexplained hypotension • Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... immediately. ❼ Give drugs ... annotate notes/drug ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... anaphylaxis (→ 3-1) Drug ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... aplastic anemia Treatment ... #diagnosis #management
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
association with CTD, drugs ... Unknown • 6-7 cases ... other processes Workup ... Organizing Pneumonia Treatment ... #management
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