17 results
Cerebral Toxoplasmosis 
- Most comrnon CNS infection in patients with AIDS 
who are not receiving appropriate
Most comrnon CNS infection ... prophylaxis Clinical ... Altered mental status ... pyrimethamine-induced hematologic ... Toxoplasmosis #Diagnosis #Overview
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... accumulation of clinical ... Assessment • Clinical ... +++: Virus (EBV, ... Lymphohistiocytosis #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia - Overview ... mutations) • Immune ... Aplastic Anemia Clinical ... Anemia #oncology #hematology ... #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
• Immune response ... transplantation CLINICAL ... specific therapy, the clinician ... Syndrome #diagnosis #management ... #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
should be based on clinical ... required until immune ... altered mental status ... , and focal neurologic ... InfectiousDiseases #Neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... • Common clinical ... Altered mental status ... Develops in the immune ... differential #diagnosis #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Syndrome (PRES) Overview ... may precede the neurologic ... Diagnosis: • Infection ... Syndrome #diagnosis #management ... #neurology
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... A state of tissue ... death Common Clinical ... Inflammatory: infectious ... Classification #diagnosis #management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... A state of tissue ... death Common Clinical ... Inflammatory: infectious ... Classification #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis Overview ... activation of an immune ... Transverse Myelitis - Clinical ... Myelitis #diagnosis #management ... #neurology #differential