15 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... and diplopia) • Vascular ... azathioprine #Behcet ... #management #signs ... #symptoms #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... Criteria: • Elevated ... , signs, and complications ... #Management #Summary ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... un lymphatic Diagnostic ... of CXR congestion ... #management #cardiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Cathepsin G release → vascular ... 5 or elevated Cr ... common • Imaging: CXR ... : >3 symptoms, or ... #management #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
intrapulmonary vascular ... Criteria: • Underlying ... Intra-pulmonary vascular ... resolution of symptoms ... #hepatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
the chest/trunk Symptoms ... - Yamaguchi criteria ... A nonpruritic macular ... #rheumatology # ... management
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
m/s • Other signs ... for definitive diagnosis ... Diagnostic criteria ... vasodilation and reduced vascular ... #management #hepatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
4) progressive muscular ... fasciculations Common Symptoms ... : months - Criteria ... : El Escorial criteria ... #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... pulse deficits vascular ... • Progressive symptoms ... vasculitis • Behcet ... #Rheumatology