27 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... Avascular necrosis ... #differential # ... diagnosis #causes ... #hematology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
intervertebral disc disease ... Raise Test - Pain ... MeralgiaParesthetica #MSK ... pathophysiology #differential ... #diagnosis #signs
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... Diagnosis Framework ... noninflammatory Signs ... constitutional symptoms ... Diagnosis #MSK #
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... osteopetrosis, avascular ... #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Sensitivity to pain ... Multiple Sclerosis Diagnosis ... Signs and symptoms ... criteria for MS
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... Tibial tuberosity pain ... tibial tuberosity Differential ... tear (similar symptoms ... #diagnosis #msk
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... ) Differential Diagnosis ... Nonsurgical abdominal pain ... #management #signs ... #symptoms #rheumatology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
mass and NO prior signs ... Differential diagnosis ... diffuse chondral disease ... #diagnosis #msk ... #rheumatology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... of CXR congestion ... coronary artery disease ... #management #cardiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Cathepsin G release → vascular ... effusions, weight gain ... common • Imaging: CXR ... : >3 symptoms, or ... initiation • Differential