22 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... and Symptoms: ... myositis overlap • Vascular ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Aortic Stenosis - Diagnosis and Stages

Clinical Presentation
- Exertional dyspnea
- Chest pain
- Palpitations
- HF Symptoms (orthopnea, PND,
Aortic Stenosis - Diagnosis ... - Late peaking systolic ... #Stages #Management ... #Signs #Symptoms ... #Cardiology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... pulse pressure: systolic ... of CXR congestion ... #management #cardiology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Failure • Dyspnea Vascular ... : • Systemic emboli ... insult due to vascular ... -> TEE • Duke Criteria ... #management #cardiology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Still's Disease Systemic ... the chest/trunk Symptoms ... A nonpruritic macular ... #rheumatology # ... management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... Criteria: • Elevated ... , signs, and complications ... #Management #Summary ... #treatment #hematology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... Multiple Sclerosis Diagnosis ... Signs and symptoms ... criteria for MS ... #management #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Cathepsin G release → vascular ... 5 or elevated Cr ... common • Imaging: CXR ... : >3 symptoms, or ... #management #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
signs/sx of inflammation ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management