14 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... - APLS • Acute ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Causes include: ... • A lack of acute ... vascular congestion ... respiratory distress syndrome ... differential #diagnosis #cardiology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... heart failure, neurologic ... renal bruit or signs ... Causes: • Vascular ... Neurologic disorders
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... Imaging: CXR- pulmonary ... Differentiation #Syndrome ... diagnosis #management #hematology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
disorder (Cardiac, pulmonary ... Impairment: • Acute ... stroke syndromes ... Lack of UMN/LMN signs ... Differential #Diagnosis #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... - ACS, AKI, acute ... WBC >100k, + lab signs ... diagnosis #management #hematology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
: • Valvular disorders ... Diagnoses: • Acute ... Coronary Syndrome ... Infarction • Pulmonary ... #cardiology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... pulse deficits vascular ... affects the skin, neurologic ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Causes of ST Segment Elevation - Differential Diagnosis Framework

STEMI:
 • Upsloping convex STE: "Pardee's sign" +
Causes of ST Segment ... STE: "Pardee's sign ... QRS complex Pulmonary ... (Eiffel Tower sign ... differential #diagnosis #cardiology